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At Fluxion, we’re passionate about delivering cell-based and cell-free solutions that facilitate the transformation of research discoveries into new ways to diagnose and treat patients. By characterizing molecular and cellular mechanisms of disease, Fluxion’s platforms help bridge the translational medicine gap, enabling rapid advances in disease research, drug discovery, and the development of diagnostic tests.

 

Cellular Analysis

BioFlux Systems

 

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Your Lab Partner for Physiological Live Cell Assays

 

Many physiological processes take place under flow conditions: blood flowing through the vasculature; cancer cells circulating throughout the body; CAR-T cells migrating through the endothelium; biofilms forming in lung infections.

It is now well established that flow has a profound impact on cell function, yet much research is still conducted in vitro without the presence of flow. BioFlux from Fluxion Biosciences gives you the ability to introduce physiological shear flow to your research and drug discovery experiments, effectively emulating in vivo conditions and revealing the true biology.

Your Lab Partner for Physiological Live Cell Assays

 

Many physiological processes take place under flow conditions: blood flowing through the vasculature; cancer cells circulating throughout the body; CAR-T cells migrating through the endothelium; biofilms forming in lung infections.

It is now well established that flow has a profound impact on cell function, yet much research is still conducted in vitro without the presence of flow. BioFlux from Fluxion Biosciences gives you the ability to introduce physiological shear flow to your research and drug discovery experiments, effectively emulating in vivo conditions and revealing the true biology.

Application Areas

Shear stress plays an important role in creating physiologically-relevant models to answer fundamental questions in cellular biology. In drug discovery and development, BioFlux helps ensure that only the most promising compounds will be passed through to clinical trials, saving tremendous time and expense versus conventional screening methods.

BioFlux Applications

Core Technology

See how BioFlux uses microfluidics to emulate physiological shear flow in an in vitro model and in a convenient well-plate format.

How it Works

BioFlux One BioFlux 200 BioFlux DCIS BioFlux 1000z
Standard Features
Fits In Hood N/A
Temperature Control
Optional
Well Plate Format
48
48/24
48/24/6
48/24/6
Microscope Configuration
Adapts to existing
Adapts to existing
Standard
Customizable
Analysis Software
Montage Software
Optional
Optional
Parallel Flow Assays
*With BioFlux Quattro add-on
24
24/96*
24/96*
24/96*
Phase Flow
Single
2-phase
2-phase
2-phase
Autofocus
Cameras
Monochrome & Color
User-defined
Epifluorescence
Filter Cubes
DAPI, GFP, RFP
User-selected
Onstage Incubator
Optional
Optional Enclosure
Fluorescence Channels
4
6
Included Objectives
10X & 20X, 5 positions
10X & 20X, 6 positions
Endpoint & Live-Cell Imaging
Automated Plate Scanning
  BioFlux One BioFlux 200 BioFlux DCIS BioFlux 1000z

Choose the best BioFlux solution for your needs

BioFlux systems come in different configurations to match laboratory and project needs. Download the product brochures and the selection guide to research your ideal system.

Download

→ BioFlux System Brochure

→ BioFlux System Selection Guide

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Resources Library & Support Center

Visit our library of application notes, webinars, live demos, posters and publications featuring BioFlux technology.

Resources Library

 

For additional support, customers can access our support site for operation technical guides, cell culture optimizations, software updates, pre-recorded training, and troubleshooting guides.

Support Center

 

Customer Spotlight

Modeling of Catheter-Associated Infection

BioFlux was used in a recent study modeling catheter-associated infection by using BioFlux microfluidics to mimick the in vivo conditions of urinary catheters. In their lab, the BioFlux 200 system has been used to evaluate the efficacy of poloxamers in reducing E. coli adhesion under controllable shear forces by exploiting BioFlux silicone microfluidic flow channels, thus mimicking the in vivo conditions of urinary catheters in terms of both flow conditions and catheter material.

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For more information

Access the Resources Library for:

 

Application Notes

Webinars

Publications

Knowledge Base

We've got you covered

Contact us for more information about BioFlux systems. 

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