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Cell Microsystems Acquires Fluxion Biosciences to Broaden Cell Analysis Product and Services Portfolio. Read the Press Release

At Fluxion, we’re passionate about delivering cell-based solutions that facilitate the transformation of research discoveries into new ways to diagnose and treat patients. By characterizing molecular and cellular mechanisms of disease, Fluxion’s platforms help bridge the translational medicine gap, enabling rapid advances in disease research, drug discovery, and the development of diagnostic tests.

BioFlux Applications

Cellular Analysis, Research, and Imaging 


Many physiological processes take place under flow conditions: blood flowing through the vasculature; cancer cells circulating throughout the body; plaque forming on teeth under the presence of saliva flow. It is now well established that physiological flow has a profound impact on many biological studies, yet much research is still conducted in vitro without the presence of flow.

BioFlux from Fluxion Biosciences gives you the ability to introduce flow to your research and drug discovery experiments, effectively emulating in vivo conditions and revealing the true biology.

Check the application pages to see how BioFlux can accelerate your live cell assays.

“Given the critical role of shear in regulating platelet adhesion and thrombus growth, these findings may have potential pathophysiological significance.” [Jackson, et al., 2006]

Oral Biofilms

Use saliva as media to replicate oral cavity for biofilm growth


Lung Biofilms

Anti-biofilm drug discovery for treatment of pulmonary diseases


Host-Pathogen Interactions

Form fungal and bacterial biofilms on epithelial monolayers in vitro


Bacterial Chemotaxis

Explore influence of genetic and morphological factors on surface motility


Mutant Screens

Use controlled shear flow on knockout mutant biofilms under physiologically relevant conditions


Medical Device Infections

PDMS and custom microfluidic plates mimic medical device infection environment


Antimicrobial Screens

Analyze effectiveness of novel antimicrobials on biofilm growth under shear flow


Adhesion Strength

Quantify biofilm adhesion and measure binding specificity in a microfluidic channel

COVID-19 Research

Study causes and treatments in COVID-19 patients


Migration & Invasion

Label-free, real-time measurements in situ


Atherosclerosis Models

Mimic arterial plaques under shear flow in vitro


Platelet Adhesion & Aggregation

Quantify platelet adhesion and aggregation area live



Explore thrombus formation using whole blood


Sickle Cell Disease

Investigate adhesive properties of sickle erythrocytes in a simulated blood environment


Stem Cells

Analyze effectiveness of novel antimicrobials on biofilm growth under shear flow


Vascular Biology

Study vascular physiology, vascular cell-blood interactions, T-cell transmigration, wound healing, angiogenesis, mechanotransduction, and more!

Immunotherapy Development

Accelerate your engineered T cell drug discovery with functional testing of adhesion and transmigration in vitro


Cell Adhesion & Rolling

Utilize time-lapse microscopy under flow to quantify cell rolling and firm adhesion


Transmigration & Migration

Temperature-controlled transmigration experiments under shear flow



Investigation of rheumatic disease under shear flow


Wound Healing

Generate more reproducible results than traditional scratch wound assays


Stem Cells

Investigate stem cell function under flow: homing, adhesion, transmigration, and differentiation

CAR-T/TCR Engineered T-Cell

Use saliva as media to replicate oral cavity for biofilm growth


Tumor Microenvironment

Control and manipulate the tumor microenvironment and test potential treatments



Examine metastasized cancer cells on endothelial monolayers and protein coatings


Cancer Cell Homing

Create 2 connected micro-environments to study cancer cell homing


Epithelial-Mesenchymal Transition

Analyze steps of cancer progression and EMT with cancer cells under shear flow


Cancer Cell Migration & Invasion

Create two adjacent micro-environments to analyze cell migration and invasion


Circulating Tumor Cells

Analyze CTC adhesion and clustering under shear flow



Examine leukocyte adhesion under shear flow conditions


Cancer Stem Cells

Analyze stem cell homing, adhesion, transmigration, and differentiation under flow

Customer Spotlight

Modeling of Catheter-Associated Infection

BioFlux was used in a recent study modeling catheter-associated infection by using BioFlux microfluidics to mimick the in vivo conditions of urinary catheters. In their lab, the BioFlux 200 system has been used to evaluate the efficacy of poloxamers in reducing E. coli adhesion under controllable shear forces by exploiting BioFlux silicone microfluidic flow channels, thus mimicking the in vivo conditions of urinary catheters in terms of both flow conditions and catheter material.


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