Proper immune function depends on the interconnected relationships of many diverse cell types. When improperly functioning, these cell-cell interactions can lead to allergy, asthma, autoimmune and infectious disease. Immune surveillance in large part occurs within the vasculature in the presence of constant flow, where cell-cell and cell-ligand interactions are influenced by in situ forces. BioFlux provides the ability to control the timing of these interactions as well as the shear rate.
Cell adhesion and rolling