Proper immune function depends on the interconnected relationships of many diverse cell types. When improperly functioning, these cell-cell interactions can lead to allergy, asthma, autoimmune and infectious disease. Immune surveillance in large part occurs within the vasculature in the presence of constant flow, where cell-cell and cell-ligand interactions are influenced by in situ forces. BioFlux provides the ability to control the timing of these interactions as well as the shear rate.

Representative applications: 

  • Transmigration migration

  • Cell adhesion and rolling

  • Wound healing


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