Antimicrobial Screening, Biofilm Formation, & Host-Pathogen Interactions
Bacteria and fungi organized into biofilms are highly refractory to known antibiotics and biocides. To develop new solutions to combat biofilms, screening technologies must be designed to grow biofilms under conditions that represent an in vivo or in situ community while maintaining the ability to add and observe the effects of compounds.
BioFlux offers a comprehensive solution for running both fundamental biology assays as well as anti-microbial compound screens.
Form fungal and bacterial biofilms on epithelial monolayers in vitro
Explore influence of genetic and morphological factors on surface motility
Use controlled shear flow on knockout mutant biofilms under physiologically relevant conditions
Medical Device Infections
PDMS and custom microfluidic plates mimic medical device infection environment
Analyze effectiveness of novel antimicrobials on biofilm growth under shear flow
Quantify biofilm adhesion and measure binding specificity in a microfluidic channel
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