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Immunology

Cell biology

 

Microbiology

Featured
Competition in Biofilms between Cystic Fibrosis Isolates of Pseudomonas aeruginosa Is Shaped by R-Pyocins
Competition in Biofilms between Cystic Fibrosis Isolates of Pseudomonas aeruginosa Is Shaped by R-Pyocins

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Biofilm Formation Potential of Heat Resistant Escherichia coli Dairy Isolates and Complete Genome of MDR Heat Resistant Strain FAM21845
Biofilm Formation Potential of Heat Resistant Escherichia coli Dairy Isolates and Complete Genome of MDR Heat Resistant Strain FAM21845

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Versatility of Biofilm Matrix Molecules in Staphylococcus epidermidis Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress
Versatility of Biofilm Matrix Molecules in Staphylococcus epidermidis Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress

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The ATP-Dependent Protease ClpP Inhibits Biofilm Formation by Regulating Agr and Cell Wall Hydrolase Sle1 in Staphylococcus aureus
The ATP-Dependent Protease ClpP Inhibits Biofilm Formation by Regulating Agr and Cell Wall Hydrolase Sle1 in Staphylococcus aureus

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Impact of Nutrient Restriction on the Structure of Listeria monocytogenes Biofilm Grown in a Microfluidic System

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Exopolysaccharide-repressing small molecules with antibiofilm and antivirulence activity against Pseudomonas aeruginosa

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AraC-Type Regulator Rbf Controls the Staphylococcus epidermidis Biofilm Phenotype by Negatively Regulating the icaADBC Repressor SarR
AraC-Type Regulator Rbf Controls the Staphylococcus epidermidis Biofilm Phenotype by Negatively Regulating the icaADBC Repressor SarR

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Bactericidal Effect of Strong Acid Electrolyzed Water against Flow Enterococcus faecalis Biofilms.
Bactericidal Effect of Strong Acid Electrolyzed Water against Flow Enterococcus faecalis Biofilms.

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Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR).
Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR).

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A high-throughput microfluidic dental plaque biofilm system to visualize and quantify the effect of antimicrobials.
A high-throughput microfluidic dental plaque biofilm system to visualize and quantify the effect of antimicrobials.

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The N-terminal part of Als1 protein from Candida albicans specifically binds fucose-containing glycans.
The N-terminal part of Als1 protein from Candida albicans specifically binds fucose-containing glycans.

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Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils.
Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils.

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New device for high-throughput viability screening of flow biofilms.
New device for high-throughput viability screening of flow biofilms.

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Karp-Cell Rolling JOVE video
Karp-Cell Rolling JOVE video
Shear-enhanced oral microbial adhesion.
Shear-enhanced oral microbial adhesion.

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The impact of the conjugative IncP-1 plasmid pKJK5 on multi species biofilm formation is dependent on the plasmid host.
The impact of the conjugative IncP-1 plasmid pKJK5 on multi species biofilm formation is dependent on the plasmid host.

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An improved medium for growing Staphylococcus aureus biofilm.
An improved medium for growing Staphylococcus aureus biofilm.

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In vitro and in vivo model systems to study microbial biofilm formation.
In vitro and in vivo model systems to study microbial biofilm formation.

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Effects of sub-minimum inhibitory concentrations of antimicrobial agents on Streptococcus mutans biofilm formation.
Effects of sub-minimum inhibitory concentrations of antimicrobial agents on Streptococcus mutans biofilm formation.

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Functional control of the Candida albicans cell wall by catalytic protein kinase A subunit Tpk1.
Functional control of the Candida albicans cell wall by catalytic protein kinase A subunit Tpk1.

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Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections.
Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections.

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The impact of recombinant fusion-hydrophobin coated surfaces on E. coli and natural mixed culture biofilmformation.
The impact of recombinant fusion-hydrophobin coated surfaces on E. coli and natural mixed culture biofilmformation.

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CcpA coordinates central metabolism and biofilm formation in Staphylococcus epidermidis.
CcpA coordinates central metabolism and biofilm formation in Staphylococcus epidermidis.

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Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils.
Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils.

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Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus.
Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus.

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Antimicrobial and antibiofilm activity of pleurocidin against cariogenic microorganisms.
Antimicrobial and antibiofilm activity of pleurocidin against cariogenic microorganisms.

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Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7
Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7

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Oncology

Stem Cells

Hematology

Featured
Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis
Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis

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Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy
Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

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Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

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Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia
Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

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The cell motility modulator Slit2 is a potent inhibitor of platelet function.
The cell motility modulator Slit2 is a potent inhibitor of platelet function.

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Using well-plate microfluidic devices to conduct shear-based thrombosis assays.
Using well-plate microfluidic devices to conduct shear-based thrombosis assays.

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Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.

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Platelet adhesion and aggregation under flow using microfluidic flow cells.
Platelet adhesion and aggregation under flow using microfluidic flow cells.

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Wound Healing Assays in Well Plate-Coupled Microfluidic Devices with Controlled Parallel Flow.
Wound Healing Assays in Well Plate-Coupled Microfluidic Devices with Controlled Parallel Flow.

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Blood-clotting-inspired reversible polymer-colloid composite assembly in flow.
Blood-clotting-inspired reversible polymer-colloid composite assembly in flow.

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Well plate microfluidic system for investigation of dynamic platelet behavior under variable shear loads.
Well plate microfluidic system for investigation of dynamic platelet behavior under variable shear loads.

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Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.
Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.

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Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.

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Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation

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Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets
Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets

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Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate.
Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate.

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